OBJECTIVE: To determine gender difference in the outcome of patients with acute myocardial infarction and unstable angina.
METHOD AND RESULTS: To assess gender difference in outcome, a retrospective case-control study was done by reviewing records of patients admitted with unstable angina and acute myocardial infarction admitted at Philippine Heart Center from January 1, 1999 to December 31, 1999. T~ere were 329 subjects. Sixty five percent were males and 35% were female. There was no difference in the proportion of males and females admitted with acute myocardial infarction and unstable angina. Females were older (p<.001), had a higher incidence of hypertension (p<.001), and were less likely to be smokers (p<.001). Women and men did not differ with respect to the use of thrombolytic agents (p=.056), the performance of coronary angiogram ( p=.105), and revascularization procedures. There was no gender difference in the in-hospital mortality (p=.470) and occurrence of complications. After adjustment for gender, older age and diabetes mellitus were noted to be factors which influenced the outcome.
CONCLUSION: There was no gender difference in the outcome and complications of patients admitted for acute myocardial infarction and unstable angina. After adjustment for gender, age and diabetes mellitus were noted to be independent predictors of in-hospital mortality. Gender did not influence the utilization of thrombolytic therapy, coronary angiography and revascularization procedures.