Female gender is an established risk factor for increased mortality and morbidity and had longer hospital stay after coronary artery bypass surgery based on studies done abroad. Similar outcome has not been documented yet among Filipinos. The general objective of this study is to determine gender difference in post-operative outcome between female and male patients who underwent coronary artery bypass surgery at the Philippine Heart Center for a period of 1 year, from January 1, 1999 to December 31, 1999. This is a retrospective study involving review of medical records of 384 patients, 92 females and 292 males included. Data were tabulated and analysed using Student t test and chi-square. Results showed no statistical significant difference in mortality rate between females and males (F=5.4%; M=2.8%, p-value=0.549). Females have statistically significant longer total length of hospital stay (F= 19± 14 days; M= 15±9.4 7 days, p-value <0.05) and postoperative hospital stay (F=11±8.80 days; M=10±3.97, p-value <0.05). While all postoperative complications between genders showed no statistical significance.