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HERDIN Record #: NCR-PHC-17032213572418 Submitted: 22 March 2017 Modified: 15 September 2017

Comparison of the New Mayo Clinic Risk Scores and clinical SYNTAX Score in predicting adverse cardiovascular outcomes following Percutaneous Coronary Intervention at the Philippine Heart Center.

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Background: Risk stratification of patients who will undergo percutaneous coronary intervention (PCI) can help physicians, patients and their families understand the risks of the procedure, thus providing an objective basis for decision-making. This study was done to compare the prognostic value of the Clinical SYNTAX Score (CSS) and New Mayo Clinic Risk Scores (NMCRS) for in-hospital and 30-day mortality and major adverse cardiovascular and cerebrovascular events (MACCE) following PCI.


Method: This is a prospective cohort study. The NMCRS for Predicting Mortality, NMCRS for Predicting MACE and CSS of all patients who underwent PCI at the Philippine Heart Center from April 1, 2011 to September 30, 2011 were computed. Patients were followed up for in-hospital and 30-day mortality and major adverse cardiovascular and cerebrovascular events (MACCE) following PCI.


Results: Of the 482 patients included in the study, 22 (4.6%) died while 37 (7.7%) had the composite endpoint (mortality, MI, emergency CABG, CVA) during hospitalization. Thirty days after PCI, 9 (2.0%) died while 19 (3.9%) had the composite endpoint. The prognostic value of NMCRS for predicting mortality, NMCRS for predicting MACE and CSS for in-hospital mortality, as measured by the c-statistic, is 0.827, 0.813, and 0.816 (p < 0.05 for all), respectively and for in-hospital composite endpoints is 0.791, 0.751, and 0.755 (p < 0.05 for all), respectively. Thirty days after PCI, the prognostic value of the NMCRS for predicting mortality, NMCRS for predicting MACE and CSS, as measured by c-statistic is 0.751 (p < 0.05), 0.760 (p< 0.05), and 0.651 (p = 0.121), respectively and for composite endpoints is 0.736 (p <0.05), 0.763 (p < 0.05), and 0.621 (p = 0.10), respectively.


Conclusion: The NMCRS for predicting mortality has better prognostic utility for in-hospital mortality and composite end-points while the NMCRS for predicting MACE better predicts 30-day mortality and composite endpoints as compared to the CSS.


 

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Heart Center Journal
Frequency
Semi-Annual
Publication Date
January-June 2016
Volume
21
Page(s)
1-9
LocationLocation CodeAvailable FormatAvailability
Philippine Heart Center Medical Library Fulltext Print Format