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HERDIN Record #: PCHRD1410090602425 Submitted: 09 October 2014 Modified: 20 September 2017

Correlation between average retinal nerve fiber layer thickness and rim area of the spectral-domain OCT with the Humphrey visual field index in eyes with glaucoma.

Andrei P. Martin,
Joseph Anthony Tumbocon,
Noel Atienza

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OBJECTIVE: To determine the correlation between the average retinal nerve fiber layer (RNFL) thickness and optic nerve head rim area (RA) measured with a spectral-domain optical coherence tomography (OCT) with the visual field index (VFI) using the Humphrey Visual Field Analyzer in glaucoma patients.
METHODS: Eighty-five consecutive patients diagnosed with glaucoma underwent spectral-domain OCT of the optic disc and Humphrey perimetry. A glaucoma specialist confirmed the presence of glaucomatous optic neuropathy based on findings in the optic nerve head photographs, OCT measurements of the RNFL and optic disc, and standard automated perimetry. The correlation of the average RNFL thickness and rim area with the VFI was determined using the Spearman's correlation coefficient analysis.
RESULTS: A total of 121 glaucomatous eyes of 85 patients were included in the study. There were 47 males and 38 females, ages ranging from 12 to 94 years. The average RNFL thickness, RA, and VFI were 67.9 ± 12.3 μm, 0.65 ± 0.3 mm2, and 56 ± 32%, respectively. The average RNFL thickness (r = 0.35) showed a stronger positive correlation with VFI than RA (r = 0.15), but the difference was not statistically significant.
CONCLUSION: The average RNFL thickness and rim area of the spectral-domain OCT demonstrated a positive correlation with the VFI of the Humphrey Visual Field Analyzer. The OCT parameters, exemplified by average RNFL and RA, were not good indicators for VFI.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Ophthalmology
Frequency
Semi-Annual
Publication Date
January-June 2014
Volume
39
Issue
1
Page(s)
45-48
LocationLocation CodeAvailable FormatAvailability
Philippine Academy of Ophthalmology Abstract External Link (View)
Philippine Council for Health Research and Development Box No. 62 Fulltext pdf (Request Document)
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