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HERDIN Record #: PCHRD08151102080551 Submitted: 15 August 2011 Modified: 02 February 2015

Types of yeasts and drug resistance of clinical isolates in the Philippines .

 G. Bulmer,
 M.  Marquez

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This study reports on the identification and fluconazole susceptibility of 579 yeast which came from patients in 16 medical establishments throughout the Philippines in 1997-98. Speciation revealed the following yeasts with percent frequency of isolation: Candida albicans (49.6%); C. parapsilosis (17.2%); C. tropicalis (14.9%); C.glabrata (6.2%); C.pelliculosa (4.3%; C. krusei (2.4%); C. guilliermondii (1.9%); Trichosporon cutaneum (1.7%); Cryptococcus neoformans (0.9%); Candida famata (0.5%); C. lusitaniae (0.2%); and Saccharamyces cerevisiae (0.2%). Assays for fluconazole sensitivity revelaed that 94% were susceptible, 5% were dose-dependent sensitive and only 1% was resistant. All isolates of Candida albicans were susceptible (one isolate being dose-dependent sensitive) to fluconazole. The only yeasts that were resistant to fluconazole were Candida guillermondii, C. glabrata and C. parapsilosis.

Publication Type
Research Project
Date
June 1, 1997-May 31, 1998

Objectives

To determine the clinically significant yeasts (genus and species) that cause disease in patients in the Philippines.2. To identify the yeast that are resistant to fluconazole.

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Philippine Council for Health Research and Development Library Abstract Print Format (Request Document)